Mewgenics Review - Nine Lives and a ...
Beginner

Mewgenics Ultimate Beginner's Guide

Master Mewgenics with essential beginner tips for tactical combat, cat breeding, positioning strategies, and survival techniques to dominate runs.

Nuwel

Nuwel

Updated Feb 9, 2026

Mewgenics Review - Nine Lives and a ...

Welcome to the chaotic world of Mewgenics, where tactical turn-based combat meets absurd cat breeding mechanics. This roguelike from the creators of The Binding of Isaac and Super Meat Boy throws you into a world with 281 achievements, thousands of unique abilities, and hundreds of enemies. The game doesn't hold your hand, but with the right foundation, you'll transform from overwhelmed newcomer to tactical mastermind.

Why Positioning Wins Battles

Backstab attacks deal drastically more damage than frontal assaults. Here's the thing - positioning your cats correctly can mean the difference between a 5-damage scratch and a devastating 15-damage critical strike.

Backstab damage comparison

Mewgenics Ultimate Beginner's Guide

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Pro Tip: Always click on the right side of your cat to control which direction they face. Enemies deal more damage from behind too, so proper facing saves precious health.

The most effective strategy combines backstab positioning with critical hit passives. When you spot abilities that increase crit chance, prioritize cats that can consistently get behind enemies.

Smart Squad Management

You don't need four cats for every excursion. Taking three cats instead allows faster leveling since you're not splitting post-battle upgrades four ways. While this makes runs harder, the accelerated growth often compensates for the smaller squad size.

Squad Size Benefits Comparison

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Environmental Mastery

Grass tiles provide a massive 50% dodge chance - always position cats in tall grass when possible. However, not all grass is created equal.

Grass tile coverage system

Mewgenics Ultimate Beginner's Guide

Water mechanics unlock creative tactical options:

  • Walk cats through water, then step on grass sprouts to grow full cover
  • Use wet hairballs to grow grass on empty tiles
  • Shock multiple enemies with electricity when they're in water
  • Extinguish burning effects by entering water

Fire tactics counter grass-camping enemies:

  • Burn enemies out of cover
  • Preemptively burn grass to deny enemy positioning
  • Use wet hairballs to extinguish fires on your cats

Combat Basics

The turn order display in the top right shows exactly when each unit acts. When facing multiple enemies in range, hover over them to see attack priority. Always eliminate or stun the enemy attacking first.

Turn order priority system

Mewgenics Ultimate Beginner's Guide

Wet hairballs offer surprising tactical value:

  • Extinguish fires at range (crucial against bomb-throwing bosses)
  • Push enemies into environmental hazards
  • Create water for grass growth
  • Stop burn damage on yourself

Movement Strategy

Don't always move on turn one. Sometimes building mana while enemies approach puts them in striking distance without exposing your cats to unnecessary damage.

Minion and Familiar Tactics

Maggots, flies, and other small familiars seem weak but serve crucial tactical roles:

  • Sacrificial positioning - trigger traps that would hurt your cats
  • Aggro drawing - waste enemy turns and tank damage
  • Controlled placement - you choose where they enter the battlefield
Familiar tactical deployment

Familiar tactical deployment

Battlefield Awareness

Switch to tactical view (hold Y on Steam Deck, hold left mouse button on PC) when battles become chaotic. This reveals:

  • Hidden enemies in bushes
  • Money and food inside rocks or garbage
  • Optimal positioning opportunities
  • Environmental hazard locations

Priority targets that fly away after a few rounds include pigeons, chickens, and small birds. These provide valuable item rewards, so eliminate them quickly.

Resource Management

Crates and garbage bags scattered around maps contain money and equipment. Break them open whenever possible - the rewards typically justify the action investment.

Catnip provides immediate health restoration. If you're one move away from catnip and still have a melee attack action, target the empty tile containing the item to grab it and potentially enable another action.

Speed and Initiative

Upgrade your speed stat (the shoe icon) to act earlier in turn order. Faster cats can eliminate threats before they attack, fundamentally changing battle dynamics.

What most players miss is that Mewgenics rewards creative environmental interaction over brute force. The key here is treating every battlefield element as a potential weapon or shield. Master these fundamentals, and you'll survive long enough to discover the deeper strategic layers that make each run feel completely unique.

Guides

updated

February 9th 2026

posted

February 9th 2026